Wilfred Ndidi and Calvin Bassey, two Super Eagles players, could face Premier League suspension as a result of their card accumulation.
After receiving five bookings, a player will have to serve out a single match.
This season, Ndidi and Bassey have each received four Premier League bookings.
When they pick up their next reservation, they will be suspended.
On Tuesday (today), Leicester City will play West Ham United at the King Power Stadium.
Ruud van Nistelrooy, the new manager, will be leading the Foxes for the first time.
On Thursday, Fulham will host Brighton & Hove Albion at the Craven Cottage.